Afiyah
Yes. Afiyah (عافية) comes from classical Arabic vocabulary and is used as a feminine given name in Arabic-speaking and Muslim communities.
No. Afiyah as a proper name does not appear in the Qur'an; however, the root and related words occur in early Islamic Arabic texts and supplications.
The exact noun 'عافية' is part of the same lexical field as words found in hadith; for instance, formulations such as 'معافى' appear in classical hadith expressions about waking secure and healthy.
Afiyah is relatively rare and considered a scholarly or classical choice rather than a mainstream modern name.
It connotes health, safety, protection from harm, and general well‑being — values emphasized in Islamic devotional language.